The Conte Center for Neuroscience Research

The Conte Center for Neuroscience Research

How does an experience, such as a stressful event or ingestion of a drug, modify the brainís intrinsic circuitry and thereby modify subsequent thoughts, feelings and behavior?

The Conte Center for Neuroscience Research at Stanford is using state-of-the-art approaches to address this question with the specific goal of understanding the detailed molecular mechanisms underlying the brainís amazing plasticity.

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The Conte Center for Neuroscience Research at Stanford uses an innovative molecular screening approach combined with sophisticated biochemical, electrophysiological, and imaging assays to elucidate novel intracellular signaling pathways that underlie different forms of synaptic plasticity and explores how these forms of synaptic plasticity modify circuit function. The new insights into synaptic plasticity mechanisms generated by the center will influence neuroscientists working on a wide range of topics related to normal and pathological brain function.

The center will also provide the research community with novel genetic tools that can be used to manipulate intracellular signaling pathways as well as novel transgenic mouse models that can be used to explore the roles of different signaling pathways and forms of synaptic plasticity in normal and pathological behaviors.

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